Archived — Canadian asset map for stem cell and regenerative medicine

References and notes

General Information

US National Institutes of Health. Regenerative Medicine. Department of Health and Human Services. August 2006. stemcells.nih.gov/info/scireport/pages/2006report.aspx/. Accessed January 21, 2011.

Endnotes

1
Stem Cell Basics. National Institutes of Health. stemcells.nih.gov/info/basics/. Accessed January 21, 2011. (Return to text)
2
Till, JE, McCulloch, EA. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiation Res. 1961; 14, 213–222; Becker AJ, McCulloch EA, Till JE. Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells. Nature. 1963; 197:452–454. (Return to text)
3
Stem Cell Network. Book Two: Strategic Plan for Second Funding Cycle 2007. Provided by Drew Lyall. (Return to text)
4
Stem Cell Network www.stemcellnetwork.ca. Accessed December 16, 2010. (Return to text)
5
(1) Stem Cell Network www.stemcellnetwork.ca. Accessed December 16, 2010; (2) Lyall, A, Isasi, R. Stem Cell Research: Perspectives from Canada. World Stem Cell Report 2010. Chapter 11. pp. 173–177. www.worldstemcellsummit.com/node/663. Accessed December 16, 2010. (3) Industry Canada. (Return to text)
6
(1) Stem Cell Network. Book Two: Strategic Plan for Second Funding Cycle 2007. Provided by Drew Lyall. (2) Industry Canada. (Return to text)
7 Canadian Scientists Transform Human Skin into Blood. www.canada.com/story_print.html?id=3793787&sponsor=. Accessed November 24, 2010. (Return to text)
8
Editorial. Betting on HSC. Nature Immunology. 2002: 3. Cited in Stem Cell Network. Book Two: Strategic Plan for Second Funding Cycle 2007. Provided by Drew Lyall. (Return to text)
9
ISI index reference. Cited in Stem Cell Network. Book Two: Strategic Plan for Second Funding Cycle 2007. Provided by Drew Lyall. (Return to text)
10
Ontario's MaRS Regenerative Medicine 2009 Industry Briefing report. www.marsdd.com/mars-library/regenerative-medicine-industry-briefing/. Accessed November 17, 2010. (Return to text)
11
Technology, talent and capital: State Bioscience Initiatives 2008. Battelle Memorial Institute and Biotechnology Industry Organization. Accessed February 23, 2011(PDF, 3,189 KB, 105 pages). (Return to text)
12
States applaud new stem cell funding. March 11, 2009. www.stateline.org/live/details/story?contentId=383210. Accessed February 23, 2011. (Return to text)
13
(1) See reference #11. Also (2) Fitzpatrick, Meagan. Canada's mantle as stem-cell leader fading, experts warn. November 2, 2010. Accessed November 24, 2010. (3) Evidence to Standing Committee on Health Nov 2, 2010. www2.parl.gc.ca/HousePublications/Publication.aspx?Language=E&Mode=1&Parl=40&Ses= 3&DocId=4750819&File=0. Accessed December 15, 2010. (Return to text)
14
All NCE funds were dedicated to U. Ottawa where the Stem Cell Network (SCN) is located. A breakdown of funds according to SCN grants across Canada would have made some difference to provincial and university funding (Figures 2 and 3), although this generally would not have been significant except for U. Ottawa. Even so, this university would still have ranked among the top five. (Return to text)
15
Stem Cell Basics. National Institutes of Health. stemcells.nih.gov/info/basics/. Accessed January 21, 2011. (Return to text)
16
Shapiro, A.M., J.R. Lakey, E.A. Ryan, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med. 2000; 343:230- 38. Cited in Lyall, A. Investment Models 3: Public Investment In Stem Cell Research In Canada. (Return to text)
17
Stem Cell Network. Stem cells for the treatment of Parkinson's disease project. www.stemcellnetwork.ca. Accessed February 7, 2011. (Return to text)
18
Cord Blood Banking (www.cordbloodassociationofcanada.com/Cord_Blood_Banking.php); Accessed January 28, 2011. (Return to text)
19
v(1) Funding only remaining obstacle to national cord blood bankwww.canada.com/health/Funding+only+remaining+obstacle+national+cord+blood+bank/
3877607/story.html#ixzz16EF5Hh40. Accessed January 28, 2011. (2) Evidence to Standing Committee on Health Nov 2, 2010. Evidence to Standing Committee on Health Nov 2, 2010 www2.parl.gc.ca/HousePublications/Publication.aspx?Language=E&Mode=1&Parl=40&Ses= 3&DocId=4750819&File=0. Accessed December 15, 2010. Note: there was an announcement on March 14, 2011 that governments had agreed to fund a national blood bank with $48 million over the next 9 years with operations expected from 2013. See "National cord blood bank to get $48M". CBC News March 14, 2011. www.cbc.ca. Accessed March 17, 2011. (Return to text)
20
www.bccancer.bc.ca/NR/rdonlyres/C88B0C23-F6F9-454B-BF33-0A6AEBADC250/57162/Headlines_2009_Spring.pdf. Accessed February 3, 2011(PDF, 1,583 KB, 4 pages). (Return to text)
21
Ontario's MaRS Regenerative Medicine Asset Map 2009. Accessed December 15, 2010 (PDF, 1,880 KB, 48 pages). (Return to text)
22
Stem Cell Banks, Libraries and Registries. Stem Cell Network. (Page 4) (97 KB, 6 pages). www.stemcellnetwork.ca/uploads/File/whitepapers/Stem-Cell-Banks-Libraries-and-Registries.pdf . Accessed February 3, 2011. (Return to text)
23
Ontario's MaRS Regenerative Medicine Asset Map 2009. Accessed December 15, 2010. (Return to text)
24
Minister Clement Announces Investments to Speed Innovations to the Marketplace www.nce-rce.gc.ca/Media-Medias/news-communiques/News-Communique_eng.asp?ID=93. Accessed January 10, 2011. (Return to text)
25
Cancer Stem Cell Consortium - Scientific Strategic Plan - 2009-2014 - 9 October 2008 (213 KB, 26 pages)www.cancerstemcellconsortium.com/uploads/PDFs/CSCC.Full.Str.Plan
%20FINAL%20REVISED%2018%20November%202008_Corrected%20Date.pdf. Accessed January 10, 2011. (Return to text)
26
Information from: International Stem Cell Research stemcells.nih.gov/research/intlresearch.asp, ISCF, International Stem Cell Forumwww.vr.se/inenglish/aboutus/internationalcollaboration/globalcollaboration/
internationalstemcellforumiscf.4.aad30e310abcb9735780006480.html. Accessed February 3, 2011. (Return to text)
27
Data were obtained from the first 50 hits from Google searches naming province, "research network", or "research group". (Return to text)
28
(1) Mapping Canadian BioPharmaceutical Assets: Academic and Hospital Research Institutes (September 2010), internal document provided by Life Science Industries Branch at Industry Canada. Citation data source: %20Performance%20Measurement(LR).pdf). Accessed January 11, 2011). (2) Report by Science-Metrix for Industry Canada 2010: Performance of Canadian Biopharmaceutical Organizations: A Scientometric and Technometric Analysis (1996–2009), dated March 31, 2010. (Return to text)
29
Canadian Scientists Transform Human Skin into Blood. www.canada.com/story_print.html?id=3793787&sponsor=. Accessed November 24, 2010. (Return to text)
30
30  Ontario—a leading centre of stem cell research. Biotechnology Focus. 2008; June: 22–25. (Return to text)
31
Nagy, A., J. Rossant, R. Nagy, et al. Derivation of completely cell culture derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci USA. 1993; 90(18): 8424-28. Cited in Lyall, A. Investment Models 3: Public Investment In Stem Cell Research In Canada. (Return to text)
32
Nagy, A., J. Rossant, R. Nagy, et al. Derivation of completely cell culture derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci U S A. 1993; 90(18): 8424-28. Cited in Lyall, A. Investment Models 3: Public Investment In Stem Cell Research In Canada. (Return to text)
33
Mapping Canadian BioPharmaceutical Assets: Academic and Hospital Research Institutes (September 2010), internal document provided by Industry Canada's Life Science Industries Branch. (Return to text)
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